Sunday, May 1, 2011

4:00 pm

GLBIO HIKE
Please join your colleagues for a pre-conference hike in the beautiful hills of Southeastern Ohio.  John Knouse (of the Athens Trails, the Athens Conservancy, and Friends of Strouds Run State  Park) will lead a 3.5 mile hike in Stroud's Run State Park – More Info

We will meet in the lobby of the Ohio University Inn at 4pm, and then will carpool to Stroud's Run State Park.

Meet at Ohio University Inn

3:00 pm - 
6:00 pm

REGISTRATION - GLBIO Conference Registration Open

Baker Center Honors Collegium Room

Monday, May 2, 2011

8:00 am

REGISTRATION - GLBIO Conference Registration Opens

Baker Center Honors Collegium

9:30 am - 11:30 am

TUTORIAL 1 “Exploring Gene Regulatory Networks Using Computational and Experimental Tools” - Abstract
Full Presentation
Drs. Kengo Morohashi, Alper Ylimaz, and Maria Katherine Mejia Guerra, The Ohio State University

Baker Center Ballroom A

TUTORIAL 2 “Gene Set Enrichment Testing with ConceptGen and LRpath, and Examining Metabolic Pathways” - Abstract
Full Presentation
Drs. Maureen Sartor and Alla Karnovsky, University of Michigan

Baker Center Ballroom B

TUTORIAL 3 “Integrative Algorithms for Cheminformatics and Chemogenomics” - Abstract
Dr. David Wild, Indiana University

Baker Center Room 242

11:30 am - 1:00 pm

LUNCH BREAK – Attendees on their own – Restaurant locations will be distributed at registration

1:00 pm - 3:00 pm

TUTORIAL 4  “Next Generation Sequencing: Biological and Technological Information Crucial to Effective Data Analysis” - Abstract
Pearlly S. Yan, Ph.D. Technical Director, The Ohio State University Comprehensive Cancer Center Nucleic Acid Shared Resource Illumina Core

Baker Center Ballroom A

TUTORIAL 5  “An Introduction to the Statistical Inference of Regulatory Networks” - Abstract
Full Presentation
Dr. Frank Emmert-Streib, Queen’s University Belfast, UK

Baker Center Ballroom B

TUTORIAL 6 “An Introduction to Bioinformatics Tools: R and Kepler” - Abstract
Full Presentation
Dr. Brian McCarthy, Ohio University.

Baker Center Room 242

3:00 pm - 3:30 pm

BREAK

3:30 pm – 4:30 pm

INVITED SESSION 1 - Abstract
“Plant Genomics and Transcriptomics Revealed by Next-Generation Sequencing Data”
Organized by Dr. Chun Liang, Miami University

Baker Center Ballroom A

3:30 pm - 4:30 pm

INVITED SESSION 2 - Abstract
“Emerging Topics in Systems Biology: Molecular Networks in Cancer”
Organized by Drs. Tim Huang and Victor Jin, Ohio State University

Baker Center Ballroom B

4:30 pm – 6:30 pm

POSTER SESSION A & RECEPTION

Walter Hall Rotunda Building
(see map)

7:00 pm – 8:00 pm

MUSIC CONCERT - Reel Bop Band  – Foot Stomping Good Time
Join the crowd at a special exclusive concert for the GLBIO 2011 Conference attendees.  Reel Bop - a powerhouse quartet of acoustic guitar, mandolin, fiddle and bass - takes on the string-pickers challenge of speed and finesse in a variety of musical styles.  They bring interpretations to jazz, bluegrass and traditional tunes.  Join Zeke Hutchison, Dean Inboden, Paul Brown and Nick Weiland for a stomping good time. 

Baker Center Ballroom A

Tuesday, May 3, 2011

9:00 am - 10:00 am

Keynote Speech

Al Hero, University of Michigan
Presentation Title: Pattern Discovery from High Throughput Biological Data - full abstract

Baker Center Ballroom A

10:00 am – 10:20 am

BREAK

10:20 am – 12:00 pm

SEQUENCE ANALYSIS (15 min talks)
Session Chair: Elizabeth Worthy, Wisconsin

OP1 # 19892 - “ Bioinformatics-driven Search for Proteins Mimic by or Interact with AvrE-family Effector Proteins from the Arabidopsis Thaliana Proteome” Stephen Opiyo, The Ohio State University - Abstract
Full Presentation

Baker Center Ballroom A

OP3 # 20000 - “Accuracy of Reading-frame Calls from Ab-initio Gene Calling Algorithms on Short Fragments” William Trimble, Argonne National Laboratory - Abstract
Full Presentation

OP5 # 20009 - “Comparative Analysis of Algorithms for Next-Generation Sequencing Read Alignment” Matthew Ruffalo, Case Western Reserve University - Abstract
Full Presentation

OP7 # 20012 - “A Signal Processing Approach for Enriched Region Detection in ChIP-Seq Data” Kun Huang, Ohio State University - Abstract

OP9 #20028 - “CarpeNovo: A Tool for Whole Genome Sequencing Clinical Diagnostics” Elizabeth Worthey, Medical College of Wisconsin - Abstract

OP11 #19962 - “Structure of the HMG Box of DNA-binding Proteins and Their Implications in Disease: Combination of Data from Sequence Alignments, NMR Structures, Disease Phenotypes and Molecular Dynamics Reveals Potential Functionality of each Amino Acid” Jeremy Prokop, University of Akron - Abstract
Full Presentation

10:20 am – 12:00 pm

PROTEIN INTERACTION/MOLECULAR NETWORKS SESSION (15 min talks)
Session Chair: Alexander Ropelewski, CMU

OP2 #19989 - “Disease Gene Prioritization Based on Topological Similarity in Protein-Protein Interaction Networks” Mehmet Erten, Case Western Reserve University - Abstract

Baker Center Ballroom B

OP4 #20031 - “Gene Prioritization by Integration” Wenhui Wang, Case Western Reserve University - Abstract

OP6 #20021 - “Network Reordering Based Integrative Expression Profiling for Microarray Classification” Xiaogang Wu, Indiana University - Abstract
Full Presentation

OP8 #19951 - “Assessing How Well a Virtual Pebble Game Predicts Ensemble Averaged Descriptions of Protein Rigidity” Luis Gonzaelz, University of North Carolina - Charlotte - Abstract
Full Presentation

OP10 #19970 - “Protein-protein Interaction Sites Prediction using Phylogenetic Substitution Models” David La, Purdue University - Abstract

OP12 #20059 “THINK Back: KNowledge-based Interpretation of High Throughput data” Fernando Farfan- University of Michigan, Computer Science and Engineering - Abstract
Full Presentation

12:00 pm - 1:30 pm

LUNCH BREAK - Attendees on their own

1:30 pm - 2:30 pm

Keynote Speech

Richard Lenski, Michigan State University
Presentation Title: Dynamics of Genome Evolution During a Long-Term Experiment with E. coli - full abstract

Baker Center Ballroom A

2:30 pm – 4:10 pm

GENE REGULATION/TRANSCRIPTION – DISEASE MODELS AND EPIDEMIOLOGY (15 min talks)
Session Chair: Matt Champion, Notre Dame

OP13 #19963 - “A Novel Iterative Splitting Random Forest (SRF) Algorithm for Analysis of High-Dimensional “Omic” data” Ms. Xiaowei Guan, Case Western Reserve University - Abstract

Baker Center Ballroom A

OP15 #19972 - “Mining the FDA Adverse Events Databases for Predictive Toxicology” Jeffrey Wiseman, Edison Biotechnology Institute - Abstract

OP17 #19979 - “Interfacing Computational Chemistry with Structural Bioinformatics: Implications for RNA and Riboswitch Drug Discovery” Jennifer Hines, Ohio University - Abstract

OP19 #19991 - “Global Spread and Evolution of Viral Hemorrhagic Septicemia Virus” Jonathon Studer, Ohio State University - Abstract
Full Presentation

OP21 #20013 - “Identifying Differential Gene Features across Large Number of mRNA-seq Experiments” Hatice Gulcin Ozer, Ohio State University - Abstract

OP23 #19969 - “Cascade Discovery in Networks”  K P Unnikrishnan, University of Michigan - Abstract

2:30 pm – 4:10 pm

PROTEIN STRUCTURE, FUNCTION, PROTEOMICS AND MASS SPECTROMETRY (15 min talks)
Session Chair: Daisuke Kihara, Purdue University
 
OP14 #20026 - “Differential Protein Expression Classifier for Biomarker Discovery for Early Detection of Human Disease Prognosis” Parminder Kaur, Case Western Reserve University - Abstract

Baker Center Ballroom B

OP16  # 19967 - “Protein Docking Prediction Using Predicted Protein-Protein Interface” Bin Li, Purdue University - Abstract

OP18  #19971 - “Multi-LZerD: Multiple Protein Docking for Asymmetric Complexes” Juan Esquivel-Rodríguez, Purdue University - Abstract
Full Presentation

OP20  #19973 - “Rapid Comparison and Multimeric Protein Complex Fitting for Low-Resolution Electron Microscopy Data” Daisuke Kihara, Purdue University - Abstract
Full Presentation

OP22  #19976 - “Patch-Surfer: Alignment Free Surface Patch-Based Ligand Binding Pocket Comparison” Dr. Lee Sael, Purdue University - Abstract
Full Presentation

OP24  #19994 - “From Molecular Phylogenetics to Quantum Chemistry: Discovering How Sesquiterpene Synthases Evolve New Functions” Troy Wymore, Pittsburgh Supercomputing Center - Abstract

4:10 pm – 4:30 pm

BREAK

4:30 pm – 5:30 pm

INVITED SESSION 3 - Abstract
“Protein Structural Bioinformatics”
Organized by Dr. Chris Bystroff, Rensselaer Polytechnic Institute 

Baker Center Ballroom B

4:30 pm - 5:30 pm

BIOIMAGING SESSION
Session Chair: Jundong Liu, Ohio University

OP43 (#19982) - “Artifacts in Mutual Information-based Image Registration: Analysis and Remedy” Dr. Jundong Liu, Ohio University - Abstract

Baker Center Ballroom A

OP44 ( #19984) - “Regularity Guaranteed Deformation Estimation in Image Registration” Mr. Bibo Shi, Ohio University - Abstract

OP45 (#19999) - “Identifying Leukemic States and Phosphorylation Differences via Edge Covers In Comparative Flow Cytometry” Mr. Ariful Azad, Purdue University - Abstract
Full Presentation

5:30 pm – 7:15 pm

POSTER SESSION B & RECEPTION

Walter Hall Rotunda Building
(see map)

7:30 pm – 8:30 pm

BANQUET

Nelson Dining Hall (see map)

8:30 pm – 9:00 pm

Keynote Speech

Michael Becich, University of Pittsburgh
Presentation Title: The Role of Biomedical Informatics in Next Generation Sequencing - full abstract

Nelson Dining Hall

Day 3: Wednesday, May 4, 2011

9:00 am - 10:00 am

Keynote Speech

Elodie Ghedin, University of Pittsburgh
Presentation Title: Comparative Genomics in Infectious Diseases and the Study of Host-Pathogen Interactions - full abstract

Baker Center Ballroom A

10:00 am – 10:20 am

BREAK

10:20 am – 11:50 am

DATABASE ONTOLOGIES AND SEQUENCE ANALYSIS (15 min. talks)
Session Chair: Jean-pierre Kocher, Mayo Clinic

OP31 #19996 - “Platform independent assessment of error in second generation sequencing data” Kevin Keegan, Argonne National Lab - Abstract
Full Presentation

Baker Center Ballroom A

OP33 #20015 - “ Fast Longest Common Subsequence Algorithm for Finding Similar Sequences in a Genome Database” Li Song, Michigan Technological University - Abstract
Full Presentation

OP35 #19964 - “Functional Coherence Assessment for Protein Groups and its Application to Pathway Assignment” Ms. Meghana Chitale, Purdue University - Abstract

OP37 #19988 - “BORA a System for the Integration of Clinical and Genomics Data” Dr. Jean-Pierre Kocher, Mayo Clinic - Abstract
Full Presentation

OP39 #19995 - “RNeo4j: A Package to Integrate R with Graph Database” Mr. Tyler Reed, Gannon University - Abstract

OP41 #20030 - “A framework for the Integration and Management of Complex Longitudinal Multi-Source Datasets from Outpatient and Inpatient Physiological Monitoring Studies” Mr. Piotr Mankowski, Brigham and Women’s Hospital - Abstract
Full Presentation

10:20 am – 11:50 am

EVOLUTION, COMPARATIVE AND POPULATION GENOMICS (15-min talks)
Session Chair: Robort Blumentha, University of
Toledo

OP32 #20050 - “In Utero Mother to Child Transmission of HIV-1 Subtype C Associated with Specific Changes in env and with Placental Localization”Dr. Samuel  Handelman, Ohio State University - Abstract

Baker Center Room 242

OP34  #20001 - “Co-occurring CTL, T-Helper and Antibody Epitopes as Potential Candidates for Multi-Epitope Vaccine Against Hepatitis C Virus”Mr. Paul Sinu, Kent State University - Abstract

OP36 #20008 - “Exploring the Impact of Virus-Host Genome Compatibility on Infectivity” Dr. Catherine Putonti, Loyola University, Chicago - Abstract
Full Presentation

OP40 #19992 - “Convergence of Genetic Influences in Predisposing Pleiotrophy” Dr. Richard McEachin, University of Michigan - Abstract
Full Presentation

OP42  #20005 - “Interpolative Multidimensional Scaling Techniques for the Identification of Clusters in Very Large Sequence Sets” Dr. Adam Hughes, Indiana University - Abstract

12:00 pm – 1:00 pm

Kitzmiller Lecture

Richard Lenski, Michigan State University
Presentation Title: Evolution in Action: Bugs and Bytes - More Info

Baker Center Ballroom A