Schedule of Events

Day 1: Monday July 9, 2007

10:00 a.m. – 5:00 p.m.

Registration
Shriver Center Lobby

10:30 a.m. – 12:00 p.m.

Tutorial I: Statistical Microarray Analysis
Mario Medvedovic, Ph.D., Assistant Professor, Cincinnati Children's Research Hospital
Shriver Center

Tutorial II: SQL and Databases
Chun Liang, Ph.D., Assistant Professor, Miami University
Shriver Center

Tutorial III: The Fundamentals of Bioinformatics
Michael Raymer, Ph.D., Wright State University
Shriver Center

Tutorial IV: The Promise of FPGA-Acceleration Processors to Bioinformatics Research
Anthony Johnson, Ph.D., University of Toledo
Shriver Center

1:30 p.m. – 3:00 p.m.

Tutorial V: High Throughput Approaches for Network Biology
David E. Hill, Ph.D., Senior Research Scientist, Associate Director of Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Harvard University
Shriver Center

Tutorial VI: RNA Structure Prediction and Comparison
Neocles Leontis, Ph.D., Professor, Bowling Green State University
Shriver Center

Tutorial VII: Mass Spectrometry, Proteomics and Bioinformatics
Michael A. Freitas, Ph.D., Ohio State University
Location: Shriver Center

Tutorial VIII: Perl for Bioinformatics
Pete Carswell, Systems Developer/Engineer, Ohio Supercomputer Center
Location: Shriver Center

3:00 p.m. – 5:00 p.m.

Reception and Poster Session I
Multi-purpose Room A, Shriver Center

6:00 p.m. – 7:00 p.m.

Keynote Speaker
Multi-purpose Room, Shriver Center

Scott Cain, PhD
Coordinator, Generic Model Organisms Database
Cold Spring Harbor Laboratory, New York
Title: The GMOD infrastructure project

7:00 p.m. – 8:30 p.m.

Dinner
Heritage Room, Shriver Center

8:30 p.m. – 9:30 p.m.

Keynote Speaker
Heritage Room, Shriver Center

Ming Li, Ph.D.
Professor, Canada Research Chair in Bioinformatics
Fellow, Royal Society of Canada
School of Computer Science
University of Waterloo
Title: Modern Homology Search

Day 2: Tuesday July 10, 2007

7:00 a.m. – 7:50 a.m.

Buffet Breakfast
Heritage Room, Shriver Center

Session 1:
Multi-purpose Rooms B and C, Shriver Center
Session Chair: Jarek Meller Ph.D., Associate Professor, Cincinnati Children Research Hospital, Presiding

8:00 a.m. – 8:20 a.m.

Genome-wide analysis of alternative promoters using a custom promoter tiling array platform, Greg Singer

8:20 a.m. – 8:40 a.m.

Predicting Protein Functions Using Decision Trees, Venkata Yedida

8:40 a.m. – 9:30 a.m.

Keynote Speaker
Multi-purpose rooms B and C, Shriver Center

Ron Elber, Ph.D.
Professor, Department of Computer Science
Director, Computational Biology Service Unit
Cornell University
Title: The network of sequence flow between protein structures

9:30 a.m. – 9:50 a.m.

Exploring Structural Implications of Positional Dependencies in Protein Sequence Alignments, Hatice Gulcin Ozer

9:50 a.m. – 10:10 a.m.

Lipid Accessibility Prediction in Membrane Proteins Using Low Complexity Regression Models, Mukta Phatak

10:10 a.m. -- 10:30 a.m.

"Word Seeker: Discovering Genome-wide Patterns", Lonnie Welch

10:30 a.m. -- 10:50 a.m.

Break

Session II
Multi-purpose Rooms B and C, Shriver Center
Session Chair: Bruce Aronow, Ph.D., Professor, Cincinnati Children Research Hospital, Presiding

10:50 a.m. – 11:10 a.m.

Predicting the functional impact of microRNAs on developmental processes, Vivek Kaimal

11:10 a.m. – 11:30 a.m.

Inferring function in non-coding DNA, Sudhindra Gadagkar

11:30 a.m. – 11:50 a.m.

Microregulation of a Master Regulatory Network, Amit U. Sinha

11:50 a.m. – 12:10 p.m.

Annotation of MicroRNA Gene Promoters in Human and Mouse by Integrative Bioinformatics Analysis, Hao Sun

12:10 p.m. – 12:30 p.m.

The GAIT System Defines an Auto-regulatory, Post-transcriptional Operon that Sequentially Restricts and Re- permits Inflammatory Gene Expression, Paul Fox

12:30 p.m. – 1:10 p.m.

Lunch
Heritage Room, Shriver Center

1:10 p.m. -- 2:00 p.m.

Keynote Speaker
Heritage Room Shriver Center

Sudhir Kumar, Ph.D.
Professor, School of Life Sciences
Director, Center for Evolutionary Functional Genomics
Arizona State University
Title: Evolutionary anatomies of disease mutations in proteins

Session III
Multi-purpose Room B and C, Shriver Center
Session Chair: Michael Wagner, Ph.D., Assistant Professor, Cincinnati Children Research Hospital Presiding

2:10 p.m. – 2:30 p.m.

Querying with the Gene Ontology and Its Annotations, Valerie V. Cross

2:30 p.m. – 2:50 p.m.

Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data, Xiangdong Liu

2:50 p.m. – 3:10 p.m.

Kolmogorov- Smirnov Based Scores for Protein Identification Using Peptide Mass Fingerprinting, Rachana Jain

3:10 p.m. – 3:30 p.m.

Comparison of Statistical Techniques for the Analysis of Metabolic Toxicological Data Derived from NMR Spectroscopy, Paul Edward Anderson

3:30 p.m. – 3:50 p.m.

A novel approach in identifying spurious and chimeric sequences in dbEST, Alex Kloft, Chun Liang

3:50 p.m. – 5:00 p.m.

Poster Session II
Multi-purpose Room A, Shriver Center

Session IV
Multi-purpose Room B and C, Shriver Center
Session Chair: Jens Lichtenberg, Ohio University

5:00 p.m. – 5:20 p.m.

“Improved human disease candidate gene prioritization using mouse phenotype”, Jing Chen

5:20 p.m. – 5:40 p.m.

“Comparison of modeling methodologies in systems biology”, Carla Purdy

5:40 p.m. – 6:00 p.m.

“Mining and Ranking Disease Associated Entities on Biomedical Semantic Web”, Ranga Chandra Gudivada

6:00 p.m. – 6:20 p.m.

“A Hybrid Computational Model of Neural Pruning as a Cause of Schizophrenia”, Jason Shifflet

6:30 p.m.-- 7:30 p.m.

Poster Session III and Reception (Continued)
Multi-purpose Room A Shriver Center

7:30 p.m. – 8:30 p.m.

Dinner
Heritage Room, Shriver Center

Keynote Speaker
Room: 123 Shriver Center

David States, Ph.D., M.D.
Professor, Department of Human Genetics
Director, Bioinformatics Program
University of Michigan
Title: Integrating Genomics and Proteomics: Using Mass Spectrometry to Annotate the Genome

Day 3: Wednesday July 11, 2007

7:00 a.m. – 7:50 a.m.

Buffet Breakfast
Heritage Room, Shriver Center

8:00 a.m. – 10:45 a.m.

Specialty Technical sessions (Concurrent sessions)

Evolutionary Biology and Diseases
Session Chair: Daniel Janies, Ph.D., Assistant Professor, Ohio State University

  • “Towards phylogenomic reconstruction”, Vinh Sy Le
  • “Faster Local Searches under the Generalized Tree Alignment Problem”, Andres Varon
  • “Novel Optimality Criteria for Phylogenetics”, Ward Wheeler
  • “Genomic and geographic surveillance of infectious disease”, Daniel Janies
  • Break
  • “A Quantitative Genotype Algorithm Reflecting H5N1 Avian Influenza Niches”, Xiu-Feng Wan
  • “Re-assortment Networks for Modeling the Evolution of Segmented Viruses”, Shahid Bokhari
  • “Personal Phylogenomics: First Human Lineage Trees Based on Large HapMap Datasets”, Andrew D. Johnson & Daniel Janies
  • Patterns of sequence changes at epitopes and adaptive evolution of host-pathogen interactions”, Helen Piontkivska

Biomedical Informatics
Session Chair: Anil Jegga, DVM, MS, Assistant Professor, Cincinnati Children Research Hospital

  • “Large scale genotype-phenotype correlation for continuous phenotypes”, Farhat Habib
  • “High-Throughput Analysis of Human Phenome to Investigate Modular “Nature of Complex Disorders”, Ranga Chandra Gudivada
  • “Frequent deletion of a 76-kb genomic DNA fragment with complement factor H-like genes CFHR3 and CFHR1 is protective against systemic lupus erythematosus (SLE) in European Americans”, Chack Yung Yu
  • “Transcriptional Genomics of Heart Development”, Sivakumar Gowrisankar
  • Break
  • “Organization of Clusters to Reveal Deeper Domain Knowledge”, Raj Bhatnagar, PhD
  • “Graph Clustering: Problems and Algorithms”, Yizhong Cheng
  • “A Local Likelihood-based Active Contour Model for Medical Image Segmentation”, Jundong Liu

Genomic Features and Algorithms
Session Chairs: Robert Blumenthal, Ph.D., Professor, University of Toledo and Quinn Li, Ph.D., Associate Professor, Miami University

  • “The exponential decay of GC-content in mammalian genomic regions subject to strand-symmetric substitution rates”, Dr. John E. Karro
  • “Toward a Methodology for Discovery of Regulatory Motifs in Plants”, Dazhang Gu
  • “Evolving Fractal Visualizations for Protein Secondary Structure Sequences”,
    Deborah Stoffer
  • “Emergence Pathways of the Gs/Gd/96-like H5N1 Avian Influenza Virus”,
    Ziming Zhao
  • “Using Fuzzy Measures for Protein Structure Alignment”, Suchitha Subramanian & Carla Purdy
  • “Integrated functional genomics to study the modulation of aboveground insect herbivores and phytopathogens by belowground microbiota”, P. Larry Phelan
  • “On the Use of Genome Rearrangement Measures for Assessing Evolutionary Relatedness”, Amit U Sinha

11:00 a.m. – 12:30 p.m.

Panel Discussion
Heritage Room, Shriver Center
“Accelerating Progress in Bioinformatics: Education, Technology, Infrastructure and Applications"

Panel Moderators:
Eric Stahlberg, Ohio Supercomputer Center and Wittenberg University
Lonnie Welch, Ohio University

Panelists:

  • Anthony R. Arment, Ph.D., Associate Professor of Biology, Central State University (Keeping Pace with the Bioinformatics Revolution in Undergraduate Education)
  • Ty Bryant, Founder, Future Path Medical, (An Entrepreneurial Perspective)
  • Kelly Hall, Ph.D., Director of Planning, Research, and Grants Clark State Community College (Questions Educators Ask When Developing New Programs Such As Bioinformatics)
  • Dr. Anthony D. Johnson, Associate Professor of Electrical Engineering and Computer Science, The University of Toledo (Hardware Accelerators For Bioinformatics)
  • Maha Nagarajan, Ph.D, Associate Professor of Biology, Wilberforce University (Science and Technology: A Nation's Future)
  • Dennis M. Sullivan, MD, MA (Ethics), Professor of Biology, Director, Center for Bioethics, Cedarville University (Overcoming Bottlenecks to Learning: Bioethics, Blogging, and the New Educational Technologies)
  • Major Leamon Viveros, USAF ARFL/HEPB, (Bioinformatics Opportunities and Challenges at the Air Force Research Lab)
  • Dean L. Zeller, Vice President, Association for Computing Machinery, Kent State University (Nifty Bioinformatics Assignments)
  • GQ Zhang, Associate Chair, Department of EECS, Case Western Reserve University (Bench to Book: Vertically Integrated Infrastructure for Proteomics Cores)

12:40 p.m. – 1:20 p.m.

Lunch
Heritage Room, Shriver Center

1:20 p.m. -- 2:00 p.m.

Keynote Speaker
Heritage Room, Shriver Center

David E. Hill, Ph.D.
Senior Research Scientist, Associate Director of Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Harvard University
Title: Interactomics: experimental and theoretical basis of biological interactions networks

2:00 p.m.

Prizes and Conference closing

International Society for Computational Biology
International Society for Computational Biology grants affiliate status to the Ohio Bioinformatics Consortium
Ohio Regional Student Group

Abstracts and Tutorials

Click on the links below for abstracts of the workshops and tutorials presented at OCCBIO 2007.
Session Abstracts
Tutorials

Previous OCCBIO Conferences

OCCBIO 2006
OCCBIO 2007
OCCBIO 2008
OCCBIO 2009